Prof. N. T. Perera

theshi

Professor

B.Sc. (Honors) (Colombo), Ph.D.(Louisiana State University, USA)

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Biosketch:

B.Sc. – University of Colombo/Sri Lanka/2004
Ph.D. – Louisiana State University/USA/2010

 

Research interest :

Synthesis of novel metal based therapeutics to curb cancer
Development of non invasive, convenient and sub cellular level detection probes for the diagnosis of cancer
Synthesis of organic ligands and inorganic complexes (Re, Pt, Zn, Cu and Ru) of biomedical relevance

 

Selected Publications:

Darshani, Taniya; Fronczek, Frank R.; Priyadarshani, V V;  Samarakoon, S; Perera, IC; Perera, Theshini. “Synthesis and Characterization of Novel Napththalene-derivatized Tridentate Ligands and their Net Neutral Rhenium Tricarbonyl Complexes  as Potential Therapeutic Agents for Lung Cancer” Polyhedron 2020

Darshani, Taniya; Thushara, Nadini; Weerasuriya, Piyumali; Fronczek, Frank R.;  Perera, IC; Perera, Theshini. “Fluorescent di-(2-picolyl) amine based drug-like ligands and their Re (CO) 3 complexes towards biological applications” Polyhedron 2020

Darshani, Taniya; Weldeghiorghis, Thomas, K.; Fronczek, Frank R.; Perera, Theshini. The first structurally characterized sulfonamide derivatized Zn (II)-dipicolylamine complexes with eight membered chelate rings. Synthetic and structural studies, Journal of Molecular Structure

Katugampala, S; Nanayakkara, C; Perera I C; Perera, T “Synthesis, Characterization and Antimicrobial Activity of Novel Copper – triazine Complexes” Bioinorganic Chemistry and Applications,  2018

Abeydeera, N; Perera I C; Perera, T “Synthesis, Characterization and BSA Binding Studies of Novel Zinc – triazine Complexes” Bioinorganic Chemistry and Applications, 2018

Subasinghe, Amali; Perera I C; Perera, Theshini, “Synthesis, Characterization, and Biological Studies of a Piperidinyl Appended Dipicolylamine Ligand and Its Rhenium Tricarbonyl Complex as Potential Therapeutic Agents for Human Breast Cancer”; Bioinorganic Chemistry and Applications, 2016

Ranasinghe, P V H K; Perera I C; Handunetti, S; Perera, Theshini, “Synthesis and Characterization of Novel Rhenium(I) Complexes towards Potential Biological Imaging Applications”; Chemistry Central Journal, 2016, 10:71

Perera, Theshini; Abhayawardhana, Pramuditha; Marzilli, Patricia A; Fronczek, Frank R.; Marzilli, Luigi G.  “Formation of a Metal-to-Nitrogen Bond of Normal Length by a Neutral Sufonamide Group within a Tridentate Ligand. A New Approach to Radiopharmaceutical Bioconjugation”; Inorganic Chemistry, 2013,52, 2412-2421

Perera, Theshini; Abhayawardhana, Pramuditha; Fronczek, Frank R.; Marzilli, Patricia A; Marzilli, Luigi G. “Iminoether Complexes of the Type, fac-[Re(CO)3(L)(HNC(CH3)OCH3)]BF4 (L = Bipyridine and Substituted Bipyridine): Synthesis and Properties”; Europen Journal of Inorganic Chemistry 2012, 618-627)

Abhayawardhana, Pramuditha; Marzilli, Patricia A;  Perera, Theshini; Fronczek, Frank R.; Marzilli, Luigi G. “New Monodentate Amidine Superbasic Ligands with a Single Configuration in fac-[Re(CO)3(5,5′- or 6,6′-Me2bipyridine)(amidine)]BF4 Complexes”; Inorganic Chemistry, 2012, 51, 7271–7283

Perera, Theshini; Fronczek, Frank R.; Watkins, S. “2,9,16,23-Tetra­kis(1-methyl­eth­yl)-5,6,11,12,13,14,19,20,25,26,27,28-dodecadehydro­tetra­benzo[a,e,k,o]cyclo­eicosene”; Acta Crystallographica Sec E Struct Rep Online. 2011, 67, 3493.

Perera, Theshini; Marzilli, Patricia A; Fronczek, Frank R.; Marzilli, Luigi G. “Several Novel N-Donor Tridentate Ligands Formed by Attack of a Terminal Amine on Coordinated Acetonitrile. Synthetic, NMR Spectral, and X-ray Crystallographic Studies of fac-Re(CO)3 Complexes”; Inorganic Chemistry 2010, 49, 2123-2131

Perera, Theshini; Marzilli, Patricia A; Fronczek, Frank R.; Marzilli, Luigi G. “NH NMR Shifts of New, Structurally Characterized fac-[Re(CO)3(polyamine)]n+ Complexes Probed via Outer Sphere H-Bonding Interactions to Anions, Including the Paramagnetic [Re(IV)Br6]2- Anion”; Inorganic Chemistry 2010, 49, 5560-5572

Perera, Theshini; Fronczek, Frank R.; Marzilli, Patricia A; Marzilli, Luigi G. “Superbasic Amidine Monodentate Ligands in fac-[Re(CO)3(5,5¢-Me2bipy)(Amidine)]BF4 Complexes: Dependence of Amidine Configuration on the Remote Nitrogen Substituents”; Inorganic Chemistry (Inorganic Chemistry 2010, 49, 7035-7045)

 

Awards:

  • NRC Merit Award – 2016
  • Research Awards – University of Sri Jayewardenepura, 2015-2017
  • Outstanding Research Scholar 2009-2010, Department of Chemistry, Louisiana State University
  • Outstanding Research Scholar 2008-2009, Department of Chemistry, Louisiana State University
  • Ingram Shield – Most Outstanding Girl of the Year 1996, Ladies’ College, Colombo

Affiliations:

Editor, Sri Lanka Association for the Advancement of Science, 2020

Hony Editor, Institute of Chemistry, Ceylon, 2018-2019

President, Section E2, Sri Lanka Association for the Advancement of Science, 2019

Vice President, Section E2, Sri Lanka Association for the Advancement of Science, 2018

General Secretary, Sri Lanka Association for the Advancement of Science, 2014-2015

Secretary, Section E2, Sri Lanka Association for the Advancement of Science, 2013

Member, Institute of Chemistry, Ceylon

 

Contact information

Telephone number : 0777614561
Web: https://scholar.google.com/citations?hl=en&user=epL8ZlsAAAAJ

Email : theshi.sjp@gmail.com