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Dr. R. M. G. C. S. K. Jayathilake

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Dr. R. M. G. C. S. K. Jayathilake

uni-id-chathuni

Senior Lecturer
B.Sc. (UoP), M.Sc. (UoP), Ph.D. (Saitama, Japan)

Research interests: Protein engineering, Food packaging, Phytochemicals in Food, Grain Technology

Email Address: chathuni@sjp.ac.lk

Research and Publications

Journal Articles

  1. C. Jayathlake, S. Kumachi, H. Arai, M. Motohashi, A. Murakami, N. Nemoto. In vitro selection of anti-gliadin single-domain antibodies from a naïve library for cDNA-display mediated immuno-PCR, Analytical Biochemistry. 589(15): (2020). https://doi.org/10.1016/j.ab.2019.113490
  2. Visvanathan, M. Qader, C.Jayathilake, B. C. Jayawardana, R. Liyanage, R. Sivakanesan. Critical review on conventional spectroscopic α‐amylase activity detection methods: merits, demerits and future prospects. Journal of the Science of Food and Agriculture. (2020) https://doi.org/10.1002/jsfa.10315
  3. C. Jayathilake, T. Terai, H. Anzai, N. Nemoto. cDNA Display Mediated Immuno-PCR (cD-IPCR): A Novel PCR-based Antigen Detection Method, Bio-Protocols, 9(24): (2019) e3457. DOI: 10.21769/BioProtoc.3457
  4. Anzai, T. Terai, C. Jayathilake, T. Suzuki, N. Nemoto, A novel immuno-PCR method using cDNA display, Analytical Biochemistry. 578 (2019) 1–6. PMID: 31028717 DOI: 10.1016/j.ab.2019.04.017
  5. Visvanathan, C. Jayathilake, R. Liyanage, R. Sivakanesan, Applicability and reliability of the glucose oxidase method in assessing α-amylase activity, Food Chemistry. 275 (2019) 265–272. PMID: 30724196 DOI: 10.1016/j.foodchem.2018.09.114
  6. C. Jayathilake, R. Visvanathan, A. Deen, R. Bangamuwage, B.C. Jayawardana, S. Nammi, R. Liyanage, Cowpea: an overview on its nutritional facts and health benefits, Journal of the Science of Food and Agriculture. 98 (2018) 4793–4806. PMID: 29656381 DOI: 10.1002/jsfa.9074
  7. Liyanage, C. Kiramage, R. Visvanathan, C. Jayathilake, P. Weththasinghe, R. Bangamuwage, B. Chaminda Jayawardana, J. Vidanarachchi, Hypolipidemic and hypoglycemic potential of raw, boiled, and sprouted mung beans (Vigna radiata L. Wilczek) in rats, Journal of Food Biochemistry. 42 (2018) 1–6. https://doi.org/10.1111/jfbc.12457
  8. Liyanage, O. Perera, G.W.A.S. Lakmini, P. Weththasinghe, R. Visvanathan, C. Jayathilake, B.C. Jayawardana, J. Vidanarachchi, R. Sivakanesan, Boiled, sprouted, and raw cowpea-incorporated diets modulate high-fat diet-induced hypercholesterolemia in rats, Food Science & Nutrition. 6 (2018) 1762–1769. PMID: 30258621 PMCID: PMC6145219 DOI: 10.1002/fsn3.727
  9. Liyanage, D. Wmmmk, C. Jayathilake, V. Rizliya, W. Swarna, B. Cj, Effect of Different Drying Methods on Antioxidant Activity of Star Fruits ( Averrhoa Carambola L .), Journal of Nutrition and Diet Supplements. 1 (2017) 1–6. Corpus ID: 52538645
  10. Visvanathan, C. Jayathilake, R. Liyanage, A simple microplate-based method for the determination of α-amylase activity using the glucose assay kit (GOD method), Food Chemistry. 211 (2016) 853–859. DOI: 10.1016/j.foodchem.2016.05.090
  11. Visvanathan, C. Jayathilake, B. Chaminda Jayawardana, R. Liyanage, Health-beneficial properties of potato and compounds of interest, Journal of the Science of Food and Agriculture. 96 (2016) 4850–4860. DOI: 10.1002/jsfa.7848
  12. Liyanage, H. Nadeeshani, C. Jayathilake, R. Visvanathan, S. Wimalasiri, Comparative Analysis of Nutritional and Bioactive Properties of Aerial Parts of Snake Gourd ( Trichosanthes cucumerina Linn.), International Journal of Food Science. (2016) 1–7. https://doi.org/10.1155/2016/8501637
  13. Liyanage, S. Gunasegaram, R. Visvanathan, C. Jayathilake, P. Weththasinghe, B.C. Jayawardana, J.K. Vidanarachchi, Banana Blossom (Musa acuminate Colla) Incorporated Experimental Diets Modulate Serum Cholesterol and Serum Glucose Level in Wistar Rats Fed with Cholesterol, Cholesterol. 9747412. (2016). PMID: 28042480 PMCID: PMC5155093 DOI: 10.1155/2016/9747412
  14. Liyanage, C. Jayathilaka, O.S. Perera, S.A. Kulasooriya, B.C. Jayawardana, S. Wimalasiri, Protein and Micronutrient Contents of Moringa oleifera (Murunga) Leaves Collected from Different Localities in Sri Lanka, Asian Journal of Agriculture and Food Sciences. 02 (2014) 264–269. Corpus ID: 129006818

Book Chapters

  1. C. Jayathlake, N. Nemoto. cDNA Display-Mediated Immuno-PCR (cD-IPCR): An Ultrasensitive Immunoassay for Biomolecular Detection. In: Posch A. (eds) Proteomic Profiling. Methods in Molecular Biology. 2261. Humana, New York, NY. (2021). https://doi.org/10.1007/978-1-0716-1186-9_19

Extended Abstracts

  1. C. Jayathilake, V. Rizliya, R. Liyanage, Antioxidant and Free Radical Scavenging Capacity of Extensively Used Medicinal Plants in Sri Lanka, Procedia Food Science. 6 (2016) 123–126. https://doi.org/10.1016/j.profoo.2016.02.028

Conference Presentations

  1. C. Jayathilake, N. Nemoto. cDNA display-mediated immuno-PCR (cD-IPCR): An ultrasensitive immunoassay for biomolecular detection. ABC-2021, October 18-20, Boston Newton, 2021
  2. C. Jayathilake, T. Terai, H. Anzai, N. Nemoto. A cDNA display mediated novel immuno-PCR method (cD-IPCR).  Next-Generation Protein Analysis and Detection (3rd edition) Ghent, Belgium. 2019
  3. C. Jayathilake, H. Anzai, T. Terai, T. Suzuki, N. Nemoto. A novel immuno-PCR method using cDNA Display. 2nd Glowing Polymer Symposium in KANTO 2019, The Polymer Society of Japan Kanto Branch, Tokyo, Japan. 2019.
  4. C. Jayathilake, S. Kumachi, H. Arai, M. Motohashi, A. Murakami, N. Nemoto. In vitro selection of anti-gliadin VHH and its application for immuno-PCR using cDNA display. 56th Peptide Symposium, Japanese Peptide Society. Tokyo, Japan. 2019.
  5. C. Jayathlake, S. Kumachi, M. Motohashi, A. Murakami, N. Nemoto. In vitro selection of anti-gliadin single-domain antibodies from an alpaca-derived VHH library with cDNA display. 55th International Peptide Symposium, Japanese Peptide Society. Kyoto, Japan. 2018.
  6. C. Jayathlake, S.  Kumachi, H. Arai, M. Motohashi, A. Murakami, N. Nemoto. Evolution of high-affinity anti-gliadin antibodies from alpaca-derived VHH library with cDNA display method. 1st Glowing Polymer Symposium in KANTO 2018, The Polymer Society of Japan Kanto Branch, Tokyo, Japan. 2018.
  7. C. Jayathilake, V. Rizliya, R. Liyanage, Analysis of Antioxidant activity of ten commonly consumed Arurvadic plants in Sri Lanka, 5th International Conference of Sabaragamuwa University Sri Lanka, Procedia Food Science   6 (2016) 123 – 126.19th – 20th November, Berjaya Hotel, Colombo 2015.
  1. C. Jayathilake, V. Rizliya , U. Premarathna, R. Liyanage. Hydrolysing Activity of Different Types of Starches Consumed in Sri Lanka, Annual Scientific Sessions, Sri Lanka Nutrition Society, Galle Face Hotel, Colombo, Sri Lanka. 2015.
  2. R. Liyanage,  , V. Rizliya, C. Jayathilake, , B. C.Jayawardana and J.K. Vidanarachchi, Effect of Banana Blossom Incorporated Experimental Diets on Serum Cholesterol and Serum Glucose Level in Wistar Rats, Sri Lanka Association for the Advancement of Science (SLAAS), University of Sri Jayawardenapura, Annual congress, 2015.
  3. R Visvanathan,C Jayathilake, R Liyanage, R Sivakanesan, Application of the Glucose oxidase assay kit (GOD/POD) in assessing amylase activity.ANRAPSL1-“Herbal Aaproaches in combating diabetes and common tropical diseases, Annual Sessions. NIFS, Kandy, Sri Lanka, 2018.
  4. R. Liyanage, C. Jayathilake, V. Rizliya, B. C.Jayawardana and J.K. Vidanarachchi, Investigating the Effect of Processed Mung Bean (Vignaradiata L.) Powder Incorporated Experimental Diets on Serum Lipid and Glucose Concentrations in Wistar Rats (Rattusnorvegicus), Sri Lanka Association for the Advancement of Science (SLAAS), University of Sri Jayawardenapura, Annual congress, 2015.
  5. V. Rizliya, C. Jayathilake and R. Liyanage, Antioxidant and α-amylase inhibitory activity of ten commonly consumed Arurvadic plants, Sri Lanka Association for the Advancement of Science (SLAAS), University of Sri Jayawardenapura, 2015.
  6. H. Nadeeshani, C. Jayathilake, V. Rizliya, R. Liyanage, S. Wimalasiri. Determination of Bioactive and Nutritional Properties of Areal Parts of Thricosanthes cucumerina Linn. 15th Asian Food Conference, Philippines, 2015.
  7. H. Nadeeshani, C. Jayathilake, V. Rizliya, R.Liyanage  and S. Wimalasiri, Determination of Bioactive and Nutritional Properties of Aerial Parts of Trichosanthes Cucumerina Linn. PGIS Research Congress 9th to 10th October 2015. University of Peradeniya.
  8. R. Liyanage, C. Jayathilake, O. S. Perera, S. A. Kulasooriya, B. C. Jayawardana, S. Wimalasiri. Protein and Micronutrient Contents of Moringa oleifera (Murunga) Leaves Collected from Different Localities in Sri Lanka, 13th Asian Food Conference, Singapore, 2013.
  9. N. T. B. Madusankha, C. Jayathilake and B. L.P. Mendis, A Landscape Analysis of Food Control Framework in Sri Lanka, Sri Lanka Association for the Advancement of Science (SLAAS), University of Sri Jayawardenapura, Annual congress, 2015.

Awards

  1. JASSO Honors scholarship for international doctoral students, Japanese Student Service Organization, Japan, 2019-2020.
  2. Research publication excellence award, National Institute of Fundamental Studies (NIFS), Sri Lanka, 2019
  3. Certificate of achievement of being a top downloaded article on Wiley Journals, 2018
  4. President’s award for scientific publications, President of Sri Lanka, 2016
  5. MedChemComm poster prize (Royal Society of Chemistry), The national workshop on separating techniques in Natural Products Research. National Institute of Fundamental Studies, Sri Lanka, 2016
   
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