Yearly Archives: 2020

Authors: J.M.N.J.Jayathilake, K.V.K Gunathilake

Journal: The European Zoological Journal

Marine toxins have received global attention for their involvement in human intoxication. Many marine phyla are well adapted to produce venoms or toxins protect themselves from associated micro fauna, predators and pathogens. Despite the toxicity, some bio toxins stand as potential drug leads in human and veterinary medicine. Amongst all marine fauna, Cnidarians are well renowned for producing bioactive peptides which are used in drug development, as they harbor various biological activities; anticancer, anti-inflammatory, immunomodulatory, radical scavenging, anti-parasitic activities, etc. Particularly, this review summarizes the bioactivities recorded from Cnidarian toxins and the possibility of using them as therapeutic agents, leading to develop into commercial products in the future.

Authors: H. S. D. Fernando, Menaka Hapugoda, Rushika Perera, William C. Black, B. G. D. N. K. De Silva

Journal: PLoS ONE

Phylogeographic relationships among global collections of the mosquito Aedes aegypti were evaluated using the mitochondrial Cytochrome C Oxidase 1 (CO1) and NADH dehydrogenase subunit 4 (ND4) genes including new sequences from Sri Lanka. Phylogeographic analysis estimated that Ae. aegypti arose as a species ~614 thousand years ago (kya) in the late Pleistocene. At 545 kya an “early” East African clade arose that continued to differentiate in East Africa, and eventually gave rise to three lineages one of which is distributed
throughout all tropical and subtropical regions, a second that contains Southeast Asian/Sri Lankan mosquitoes and a third that contains mostly New World mosquitoes. West African collections were not represented in this early clade. The late clade continued to differentiate
throughout Africa and gave rise to a lineage that spread globally. The most recent branches of the late clade are represented by South-East Asia and India/Pakistan collections. Analysis of migration rates suggests abundant gene flow between India/Pakistan and the rest of the world with the exception of Africa.

Authors: Michelle C. Langley, Noel Amano, Oshan Wedage, Siran Deraniyagala, M.M Pathmalal, Nimal Perera, Nicole Boivin, Michael D. Petraglia, Patrick Roberts
Journal: SCIENCE ADVANCES

Archaeologists contend that it was our aptitude for symbolic, technological, and social behaviors that was central to Homo sapiens rapidly expanding across the majority of Earth’s continents during the Late Pleistocene. This expansion included movement into extreme environments and appears to have resulted in the displacement of numerous archaic human populations across the Old World. Tropical rainforests are thought to have been particularly challenging and, until recently, impenetrable by early H. sapiens. Here, we describe evidence for bow-and-arrow hunting toolkits alongside a complex symbolic repertoire from 48,000 years before present at the Sri Lankan site of Fa-Hien Lena—the earliest bow-and-arrow technology outside of Africa. As one of the oldest H. sapiens rainforest sites outside of Africa, this exceptional assemblage provides the first detailed insights into how our species met the extreme adaptive challenges that were encountered in Asia during global expansion

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Authors: H.S.D. Fernando, Menaka Hapugoda, Rushika Perera, William C. Black and B.G.D.N.K. De Silva

Journal: insects

In Sri Lanka, dengue is the most serious arboviral disease. Recent increases in dengue cases suggest a higher infection rate and spread of the disease to new areas. The present study explores gene flow patterns of Ae. aegypti, the main vector of dengue disease, among 10 collection sites including major ports and inland cities using variations at 11 microsatellite loci. Discriminant analysis of principal components (DAPC) and k-means clustering estimated eight genetic clusters. Analysis of Molecular Variance (AMOVA) estimated equal variances among cities and among collections in Colombo, Sri Lanka. Significant evidence, although weak, was detected for isolation by distance. Analysis of gene flow rates and directions using MIGRATE-n indicated that populations throughout the island served as a source of immigrants for Colombo with abundant gene flow among major commercial cities in Sri Lanka, which appear to receive migrant mosquitoes from throughout Sri Lanka. The observed patterns probably arise through human movement of Ae. aegypti during commerce from throughout Sri Lanka into Colombo increasing the risk of spread. The patterns uncovered in this study are significant for global health as Sri Lanka is situated along a key international shipping route